The Silva Pattern-based Classification for HPV-associated Invasive Endocervical Adenocarcinoma
Background
- Silva pattern-based classification for human papilloma virus–associated invasive adenocarcinoma
- Reliable system to predict risk of lymph node metastasis and recurrences
- Synoptic reports
- College of American Pathologists (CAP)
- International Collaboration on Cancer Reporting (ICCR)
- National Comprehensive Cancer Network (NCCN) guidelines
- “emergent concept”
::: aside International Journal of Gynecological Pathology: March 2021 - Volume 40 - Issue - p S48-S65 :::
Definitions
Clinico-pathologic features
Pattern A
Pattern B
Pattern C
Algorithm
Treatment
- Pattern A
- Conservatively with conization with negative margins and no lymph node dissection
- Pattern B with LVI
- SLN mapping or limited LN sampling
- Pattern C
- Standard surgical treatment including SLN sampling or LN dissection
The Silva Pattern-based Classification for HPV-associated Invasive Endocervical Adenocarcinoma